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A variety of media, supplemental media components, and reagents suitable for cell culture operations and processes. Products include fully prepared media as well as antibiotics, growth factors, contamination detection and removal reagents, cell dissociation reagents, and more.
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Calhex 231 hydrochloride is a selective negative allosteric modulator of the calcium-sensing receptor (CaSR) used as a research reagent to investigate CaSR-mediated signaling and related pathologies. It blocks Ca2+-induced inositol phosphate accumulation and has been applied in cellular and in vivo studies of traumatic hemorrhagic shock and diabetic cardiomyopathy.
Selective negative allosteric modulation of CaSR.
Reported IC50 ≈ 0.39 μM for human CaSR activity.
High chemical purity (~99.8%) suitable for research use.
Solid form, soluble in DMSO for biological assays.
Storage stability in solvent: -80°C up to 6 months, -20°C up to 1 month.
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Calhex 231 hydrochloride is the hydrochloride salt of Calhex 231, a negative allosteric modulator of the calcium-sensing receptor (CaSR) used in biochemical and cellular research. Supplied as a high-purity white to off-white solid, it is intended for in vitro studies and should be stored at -20°C in a sealed container.
Negative allosteric modulator of the CaSR.
CAS number 2387505-78-2.
Molecular formula C25H28Cl2N2O; molecular weight 443.41.
High purity (≈99.8%) suitable for research applications.
White to off-white solid; hydrochloride salt form.
Store sealed at -20°C and protect from moisture.
Used in studies of CaSR signaling, including trauma and cardiomyopathy models.
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HUMAN FIBROBLAST GROWTH FACTOR-BASIC, SF9 (RECOMBINANT): Recombinant Human Glycosylated Fibroblast Growth Factor-acidic Source: Baculovirus Background: Single-chain polypeptide growth factor that plays a significant role in the proce...
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CD68 protein is essential for phagocytic activities in tissue macrophages including lysosomal metabolism and interactions with cells and pathogens It binds to lectins or selectins aiding targeted migration of specific macrophage subsets CD68 s rapid recirculation from endosomes and lysosomes to the plasma membrane allows macrophages to crawl or interact with selectin-bearing substrates and other cells CD68 Protein Human (sf9 His) is the recombinant human-derived CD68 protein expressed by Sf9 insect cells with C-His labeled tag
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L-ornithine ((S)-2 5-Diaminopentanoic acid) has an antifatigue effect by increasing the efficiency of energy consumption and promoting the excretion of ammonia It is one of the key reactants in the urea cycle
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